Selected publications

Opto-RhoGEFs, an optimized optogenetic toolbox to reversibly control Rho GTPase activity on a global to subcellular scale, enabling precise control over vascular endothelial barrier strength.

Mahlandt EK, Palacios Martínez S, Arts JJ, Tol S, van Buul JD, Goedhart J. (2023) eLife, doi:10.7554/eLife.84364

Single-cell imaging of ERK and Akt activation dynamics and heterogeneity induced by G-protein-coupled receptors

Chavez-Abiega S, Grönloh MLB, Gadella Jr. TWJ, Bruggeman FJ, Goedhart J (2022) Journal of Cell Science, doi:10.1242/jcs.259685

A turquoise fluorescence lifetime-based biosensor for quantitative imaging of intracellular calcium

van der Linden FH, Mahlandt EK, Arts JJG, Beumer J, Puschhof J, de Man SMA, Chertkova AO, Ponsioen B, Clevers H, van Buul JD, Postma M, Gadella Jr. TWJ, Goedhart J (2021) Nature Communications, doi:10.1038/s41467-021-27249-w

SuperPlotsOfData—a web app for the transparent display and quantitative comparison of continuous data from different conditions

Goedhart J (2021) Molecular Biology of the Cell, doi:10.1091/mbc.E20-09-0583

Robust and Bright Genetically Encoded Fluorescent Markers for Highlighting Structures and Compartments in Mammalian Cells

Chertkova AO, Mastop M, Postma M, van Bommel N, van der Niet S, Batenburg KL, Joosen L, Gadella Jr. TW J, Okada Y, Goedhart, J (2020) bioRxiv, doi:10.1101/160374

Structure-guided evolution of cyan fluorescent proteins towards a quantum yield of 93%

Goedhart J, von Stetten D, Noirclerc-Savoye M, Lelimousin M, Joosen L, Hink MA, van Weeren L, Gadella Jr. TWJ, Royant A (2012) Nature Communications, doi:10.1038/ncomms1738